Risk Stratification

A newly published study funded by the National Institutes of Health (NIH) has revealed a promising diagnostic tool capable of accurately predicting which seemingly healed diabetic foot ulcers (DFUs) are at high risk of reopening. By measuring trans-epidermal water loss (TEWL)—an indicator of skin barrier function—researchers found that wounds with elevated TEWL were substantially more likely to recur. The results, which will be published in the journal Diabetes Care, suggest that incorporating TEWL measurements into standard wound-care protocols could greatly enhance clinicians’ ability to ensure truly complete wound closure and reduce life-long risks associated with DFUs, including lower-limb amputations and premature mortality.

Scientists have identified a specific gut microbiota profile that can help forecast future heart attacks and major cardiovascular events in patients with coronary heart disease (CHD). The findings, published in the European Heart Journal, provide promising evidence that the gut microbiome may become a valuable tool in personalizing treatment and improving preventive strategies in cardiovascular care.