clinical implications

Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by CAG repeat expansions in the huntingtin gene. This condition leads to severe motor, cognitive, and emotional difficulties, typically manifesting in mid-adulthood. Recent advancements in neuroimaging and the identification of biomarkers have opened pathways for early detection, offering opportunities for targeted interventions before clinical symptoms emerge. Understanding these developments is crucial for shaping future prevention trials and enhancing therapeutic strategies for at-risk individuals and potentially other neurodegenerative conditions.